Clinical Topics & Methods Category

Familiality and Heritability of Binge Eating Disorder: Results of a Case-Control Family Study and a Twin Study: Provided by International Journal of Eating Disorders

0.5 CE Hours
34 members have taken this course

This course has been retired. We regularly update our course catalog to ensure relevance.

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About the Course

Abstract
Objective:
To estimate the familiality and heritability of binge eating disorder (BED).
Method:
We used a new ACE structural equation model to estimate heritability from a case-control family study of BED conducted in the Boston area. The sample consisted of 150 overweight/obese probands with lifetime BED by DSM-IV criteria, 150 overweight/obese probands without lifetime BED, and 888 of their first-degree relatives. We compared our findings with those from a study of binge eating (in the absence of compensatory behaviors) among 7,831 Norwegian twins.
Results:
The prevalence of BED differed by sex and by age. In the case-control family study, BED was found to aggregate in families, and heritability was estimated as 57% (CI: 30-77%). Including shared environment did not substantially improve the model’s fit, nor did allowing sex-specific heritability. Findings from the twin study were similar.
Conclusion:
BED appears to aggregate in families and have a significant genetic component.

This course is based on the reading online article, Familiality and Heritability of Binge Eating Disorder: Results of a Case-Control Family Study and a Twin Study: Provided by International Journal of Eating Disorders created by Kristin N. Javaras, PhD et al

Publication Details

Journal/Publisher: International Journal of Eating Disorders/Wiley InterScience
Publication Date: March 2008, Volume 41, Issue 2

Course Material Authors

Course Material Authors authored the material only, and were not involved in creating this CE course. They are identified here for your own evaluation of the relevancy of the material this course is based on.

Kristin N. Javaras, PhD
Department of Biostatistics, Harvard School of Public Health, Boston, Massachusetts and Biological Psychiatry Laboratory, McLean Hospital, Belmont, Massachusetts
Nan M. Laird, PhD
Department of Biostatistics, Harvard School of Public Health, Boston, Massachusetts
Ted Reichborn-Kjennerud, MD
Division of Mental Health, Norwegian Institute of Public Health, Oslo, Norway and Institute of Psychiatry, University of Oslo, Norway
Cynthia M. Bulik, PhD
Department of Psychiatry, School of Public Health, University of North Carolina at Chapel Hill, North Carolina and Department of Nutrition, School of Public Health, University of North Carolina at Chapel Hill, North Carolina
Harrison G. Pope Jr, MD
Biological Psychiatry Laboratory, McLean Hospital, Belmont, Massachusetts and Department of Psychiatry, Harvard Medical School, Boston, Massachusetts
James I. Hudson, MD, ScD
Biological Psychiatry Laboratory, McLean Hospital, Belmont, Massachusetts and Department of Psychiatry, Harvard Medical School, Boston, Massachusetts

Course Creator

Keith Gibson, Ph.D.

Target Audience

This course is recommended for health care professionals, especially psychologists, counselors, social workers, addiction counselors, officers of the court, and nurses who seek knowledge about suicidal behavior in adolescents. It is appropriate for all levels of participants' knowledge.

Learning Objectives

After taking this course, you should be able to:

  1. 1 Explain that ACE models partition the variance of a trait into three sources: additive genetic effects (A), shared or common environment effects (C), and unique environment effects (E).
  2. 2 Recognize that ACE models, although most commonly used with twin data, can also be used with more general family data.
  3. 3 State whether binge eating disorder is heritable.

Disclosure to Learners

CE Learning Systems adheres to the ACCME's Standards for Integrity and Independence in Accredited Continuing Medical Education. Any individuals in a position to control the content of a CE activity – including faculty, planners, reviewers, or others ― are required to disclose all relevant financial relationships with ineligible entities (formerly known as commercial interests).

The following relevant financial relationships have been disclosed by this activity's planners, faculty, and the reviewer:

Planners and Reviewers

The planners of this activity have reported that they have no relevant financial relationships.

Material Authors

Any relevant financial disclosures for course material authors can be found in the article.

Course Creator

Keith Gibson, Ph.D. – There are no known relevant financial relationships to disclose.

Commercial support

There is no commercial support for this distance-learning course.

$9

Your CE Credits

0.5 CE Hours CE Approvals CE Approvals

Course Details

Reading Online
Course 101374

Availability

This course is retired. It is no longer available.

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